Trade name of the drug: WOBENZYM ®

Dosage form : enteric-coated tablets (dragees).

Compound:
Active substances:
Pancreatin 345 prot. Eur.Pharm.-Units, papain 90 F.I.P-Units, rutoside 3 H 2 O 50.00 mg, bromelain 225 F.I.P-Units, trypsin 360 F.I.P-Units. lipase 34 F.I.P-Units. amylase 50 F.I.P- Units, chymotrypsin 300 F.I.P-Units.
Excipients:
Lactose, corn starch, magnesium stearate, stearic acid, purified water, colloidal silicon dioxide, talc.
Sucrose, talc, methacrylic acid-methyl methacrylate copolymer, shellac, titanium dioxide, white clay, yellow-orange dye S (E110), crimson dye 4R (E124), povidone, macrogol 6000, triethyl citrate, vanillin, bleached wax, carnauba wax.

Description: Round biconvex tablets with a smooth surface, with a characteristic odor, colored red-orange. Variations in the color intensity of the outer shell from red-orange to red are allowed.

Pharmacotherapeutic group: anti-inflammatory, immunomodulatory agent.
ATX code E03AX

Pharmacological properties
WOBENZYM is a combination of natural enzymes of plant and animal origin. Entering the body, enzymes are absorbed in the small intestine by resorption of intact molecules and, by binding to transport proteins in the blood, enter the bloodstream. Subsequently, enzymes, migrating along the vascular bed and accumulating in the area of ​​the pathological process, have an immunomodulatory, anti-inflammatory, fibrinolytic, decongestant, antiplatelet and secondary analgesic effect.
WOBENZYM has a positive effect on the course of the inflammatory process, limits the pathological manifestations of autoimmune and immune complex processes, and has a positive effect on the body’s immunological reactivity. Stimulates and regulates the level of functional activity of monocytes-macrophages, natural killer cells, stimulates antitumor immunity, cytotoxic T-lymphocytes, and phagocytic activity of cells.
Under the influence of WOBENZYME, the number of circulating immune complexes decreases and membrane deposits of immune complexes are removed from tissues.
WOBENZYME reduces the infiltration of the interstitium by plasma cells. Increases the elimination of protein debris and fibrin deposits in the area of ​​inflammation, accelerates the lysis of toxic metabolic products and necrotic tissue. Improves the resorption of hematomas and edema, normalizes the permeability of vascular walls.

WOBENZYME reduces the concentration of thromboxane and platelet aggregation. Regulates the adhesion of blood cells, increases the ability of red blood cells to change their shape, regulating their plasticity, normalizes the number of normal discocytes and reduces the total number of activated forms of platelets, normalizes blood viscosity, reduces total quantity microaggregates, thus improving microcirculation and rheological properties of blood, as well as the supply of tissues with oxygen and nutrients.

WOBENZYM reduces the severity side effects associated with taking hormonal drugs (hypercoagulation, etc.).

WOBENZYM normalizes lipid metabolism, reduces the synthesis of endogenous cholesterol, increases the content of high-density lipoproteins, reduces the level of atherogenic lipids, and improves the absorption of polyunsaturated fatty acids.

WOBENZYM increases the concentration of antibiotics in the blood plasma and the site of inflammation, thus increasing the effectiveness of their use. At the same time, enzymes reduce the unwanted side effects of antibiotic therapy (dysbacteriosis), by improving the environment.
WOBENZYME regulates nonspecific defense mechanisms (production of interferons), thereby exhibiting antiviral and antimicrobial effects.

Indications for use
Applicable in complex therapy the following diseases:

Prevention
microcirculation disorders, post-stress disorders, as well as failure of adaptation mechanisms. Prevention of side effects of hormone replacement therapy, hormonal contraception. During surgical interventions to prevent infectious complications and adhesions.

Contraindications
Individual intolerance to the drug. Diseases associated with an increased likelihood of bleeding (hemophilia, thrombocytopenia, etc.). Carrying out hemodialysis. Children's age up to 5 years.

Use during pregnancy and lactation
Pregnancy and lactation are not a contraindication for the use of the drug, however, pregnant women should take WOBENZYM under the supervision of a physician.

Directions for use and dose
The tablets should be taken orally, at least 30 minutes before meals, without chewing, with water (200 ml.).
Adults
Depending on the activity and severity of the disease, WOBENZYM is taken in a dose of 3 to 10 tablets 3 times a day. In the first three days of taking the drug, the recommended dose is 3 tablets 3 times a day.
With average disease activity, WOBENZYM is prescribed in a dose of 5-7 tablets 3 times a day for 2 weeks. In the future, the dose of WOBENZYM should be reduced to 3-5 tablets 3 times a day, course 2 weeks.
If the disease activity is high, WOBENZYM is prescribed in a dose of 7-10 tablets 3 times a day for 2-3 weeks. Subsequently, the dose of WOBENZYM is reduced to 5 tablets 3 times a day, the course is 2-3 months.
For chronic long-term diseases, WOBENZYM can be used according to indications in courses of 3 to 6 months or more.
In order to increase the effectiveness of antibiotics and prevent dysbacteriosis, WOBENZYM should be used throughout the entire course of antibiotic therapy in a dose of 5 tablets 3 times a day. After stopping the course of antibiotics, to restore the intestinal microflora (biocenosis), WOBENZYM should be prescribed 3 tablets 3 times a day for 2 weeks.
As a “cover” therapy during chemotherapy and radiation therapy, WOBENZYM should be used in a dose of 5 tablets 3 times a day until the course of chemotherapy and radiation therapy is completed; to prevent infectious complications, improve the tolerability of basic therapy and improve the quality of life.
When using WOBENZYME for preventive purposes the dose of the drug is 3 tablets 3 times a day, the course is 1.5 months, repeated 2-3 times a year.

Children
Children from 5 to 12 years old - 1 tablet per day per 6 kg of child weight. From 12 years old according to the adult scheme. The dosage and duration of treatment depend on the severity of the disease and are determined by the doctor.

Side effect
WOBENZYME is well tolerated by patients. In most cases, no side effects, withdrawal syndrome, or addiction were observed even with long-term treatment with high doses. IN in some cases There are minor changes in the consistency and smell of feces, skin rashes in the form of urticaria, which disappear when the dose of the drug is reduced or discontinued.
If other adverse reactions not noted in the instructions occur, it is recommended to stop taking the drug and consult a doctor.

Overdose
There are no known cases of drug overdose.

Interaction with others medicines
When taking WOBENZYM simultaneously with other drugs, cases of incompatibility have not been described.

Special instructions
In the case of infectious processes, WOBENZYM does not replace antibiotics, but increases their effectiveness by increasing the concentration in the blood plasma and the site of inflammation.
It should be borne in mind that at the very beginning of taking the drug, the symptoms of the disease may worsen; in such cases, treatment should not be interrupted, but a temporary reduction in the dose of the drug is recommended.
The drug is not a doping and does not have any negative influence driving a car and performing work that requires high speed mental and physical reactions.

Release form
The tablets are packed in blisters of 20 pcs. and placed in cardboard boxes of 2, 10 blisters with attached instructions for use.
Packaging - 800 tablets contains tablets in high-density polyethylene bottles with included instructions.

Storage conditions
List B.
In a dry, dark place at a temperature of 15 to 25°C, out of the reach of children.

Best before date
Duration 2.5 years. Do not use after the stated expiration date.

Conditions for dispensing from pharmacies
Over the counter.

Manufacturer
MUKOS Pharma GmbH and Co., Germany,
produced by MUKOS Emulsions GmbH, Germany

For additional information contact the General Representative Office of MUKOS Pharma in Russia:
St. Petersburg, Millionnaya str., 11, Moscow

Enzyme therapy in many countries is a separate area of ​​medical science. The need for enzyme therapy arose due to the frequent use of aggressive chemicals. They help cope with the disease, but have a lot of side effects. To reduce the severity of these effects and increase the therapeutic significance of treatment, enzyme-containing drugs are used.

A popular remedy used in almost every branch of medicine is Wobenzym. From European medical societies There are no recommendations for its use. In a number of countries it is offered as a dietary supplement. But the use of this remedy shows good practical results as an auxiliary line of therapy. Wobenzym is used in gynecology, surgery, ophthalmology, pediatrics and other areas of medical practice.

Description

This medicine is a carefully calibrated combination of plant and animal enzymes with proteolytic (targeted protein breakdown) activity. The drug is of natural origin. Its plant and animal components coexist perfectly within one tablet and complement each other’s effect.

A deeply thought-out combination of enzymatic components allows this medicine to be classified in the group of anti-inflammatory and immunomodulatory agents.

Systemic effects of the drug include:

• Antiaggregant.
• Fibrinolytic.
• Immunomodulatory.
• Decongestant.
• Secondary analgesic effect.

Thanks to the first action, the ability of platelets to stick together is reduced, and blood clots do not form inside the bloodstream. Fibrinolysis involves the breakdown of the main structure-forming component of blood clots - fibrin. This allows you to fight existing thrombosis.

The active substances of Wobenzym have a multidirectional effect on the biochemistry of organs and tissues of the human body.

How does it work?

Wobenzym is available in tablet form. These are round, convex, brightly colored tablets. Each pill of the drug is covered with a red enteric coating. The shell allows the drug to penetrate the intestines, passing through the aggressive environment of the stomach without damaging its components.

Penetrating through the intestinal wall and binding to antiproteases (transport proteins) in the blood, the components of the drug indirectly participate in many processes:

1. Regenerative, including in the formation of scars.
2. In the immune response, converting the reaction from inflammatory to anti-inflammatory.
3. Affects growth factors and hormones.

Some of the enzymes do not leave the intestines, but are used to improve digestive functions. By normalizing the process of food digestion, not only does the digestibility of proteins, fats and carbohydrate foods improve, but also intestinal microbiocinosis is restored.

The components of Wobenzym can affect the mediator of platelet aggregation (sticking together) (thromboxane). This prevents the formation of blood cells from settling on the walls of blood vessels. The medication reduces the level of active platelets in the blood. This has a positive effect on blood rheology. In addition, the drug is able to improve the plasticity of red blood cells, and therefore the transport of oxygen to tissues.

Thanks to the competent combination of the components that make up the drug, the severity of side effects from the main treatment (including hormones and antibacterial agents) is reduced. To some extent, this medicine can be classified as an antioxidant, because it can prevent fat peroxidation and reduce the level of low-density lipoproteins.

The drug has a wide list of indications, a minimum of side effects and contraindications, and one significant drawback - the price.

Application in gynecology

In gynecological practice, the drug is widely used for the treatment of inflammatory diseases of the reproductive organs, both in the acute period and chronic sluggish conditions. It can be prescribed:

• To preserve pregnancy in case of threat of self-abortion.
• In case of recurrent miscarriage in the anamnesis.
• For endometritis, vaginitis, endocervicitis, adnexitis, salpingoophoritis and salpingitis.
• For adhesions in the tissues of the uterus and fallopian tubes (for the prevention of infertility).
• In the postoperative period.
• As a prevention of side effects during HRT during menopause.

Almost all inflammatory diseases of the uterus and its appendages, in the case of chronicity of the process, are accompanied by adhesive changes in the mucous lining of organs, disruption of the menstrual cycle and reproductive function, including infertility. Adhesive processes owe their origin to long-term infectious and inflammatory processes in the uterus and appendages, which lead to a decrease in local tissue resistance to the effects of adverse factors. As a result of inflammation, tissue trophism deteriorates, swelling develops, and, ultimately, adhesions form.

The drug helps restore blood microcirculation, the functioning of adaptation mechanisms and counteract stress. It normalizes the immune response at the local level, reduces the severity of edema and prevents the adhesive process. Its use in complex therapy can improve the effect of antibacterial treatment and reduce the severity of the side effects of antibiotics. Accordingly, treatment time is reduced and healing processes are accelerated.

The pronounced anti-inflammatory effect of this medicine allows one to accelerate the course of reparative processes, thanks to which specialists are able to preserve reproductive function in young patients after interventions on the female genital organs. As an adjuvant, Wobenzym can be prescribed for endometriosis.

Treatment with this remedy can last from 2 weeks (as a prevention of side effects of antibacterial therapy) to a year (for the treatment of serious adhesive changes). The duration of the course of therapy is prescribed by the doctor. The dose of the drug is also recommended by the attending physician.

According to the official annotation, the drug can be prescribed in quantities from 3 to 10 tablets per dose (depending on the diagnosis). Take the medicine three times a day.

Contraindications and side effects

Considering the natural origin of the product, it is not surprising that it is well tolerated by patients. With a long course of treatment, addiction does not develop to it; after cessation of use, no cases of withdrawal syndrome have been recorded.

In rare cases, an allergic reaction (urticaria) is possible, which goes away after reducing the dose of the medication. However, doctors usually warn patients that if any negative reaction develops, even not described in the instructions, they need to stop taking the drug and contact the specialist who prescribed it.

The drug is not prescribed if there is intolerance to any of its components and at the time of hemodialysis. Wobenzym is not approved for use in early childhood(up to 5 years). As an antiplatelet drug, the drug is contraindicated in persons with increased bleeding (hemophilia or thrombocytopenia).

Additional information

Wobenzym is an over-the-counter drug that can be freely purchased at any pharmacy. However, the instructions for use of the medicine do not recommend using it for self-medication.

Some important treatment features:

1. At the beginning of the therapeutic course, the patient may experience increased symptoms of the disease. In this case, you need to consult a doctor. Usually the drug is not discontinued, the dose is simply reduced. This is enough to normalize the patient’s well-being.


2. In the treatment of inflammatory diseases of the pelvic organs, Wobensin cannot replace basic therapy (antibiotics, drugs to restore vaginal biocinosis). It is only a means of accelerating recovery and preventing adhesions.
3. The drug is not a doping drug, does not conflict with other medications, and the official annotation does not report anything about cases of its overdose.
4. The medicine is approved for use by persons performing responsible work that requires increased attention and high reaction speed (for example, drivers).

During the period of bearing a baby and when feeding it with mother's milk, Wobenzym is not prohibited for use. But it must be prescribed carefully and taken under medical supervision.

Thank you

The site provides background information for informational purposes only. Diagnosis and treatment of diseases must be carried out under the supervision of a specialist. All drugs have contraindications. Consultation with a specialist is required!

Wobenzym is a drug that has both decongestant and anti-inflammatory, fibrinolytic, as well as immunomodulatory properties. This pharmaceutical product has found wide application in various branches of medicine, including gynecology. In most cases, this drug is used in this industry along with antibiotic and hormonal agents. This drug helps reduce the development of side effects of these groups of drugs.

If we consider directly the gynecological diseases in the fight against which Wobenzym is used, then these are urethritis, colpitis, cervicitis, cystitis, adnexitis and many others. You cannot do without the help of this pharmaceutical in the case of various inflammatory processes of the uterus and its appendages. For example, with adnexitis, the patient is prescribed five to eight tablets of this drug three times a day. The course of treatment is fourteen days. For endometriosis, the patient should take five tablets of this drug for two months. After about a month and a half, the course of therapy will need to be repeated. If you have thrombophlebitis, you also need to take five tablets three times a day, but only for two to three weeks.

Quite often, Wobenzym is also used to treat sexually transmitted diseases. These include chlamydia, ureaplasmosis, mycoplasmosis and some others. In this case, you should take five Wobenzym tablets three times a day throughout the entire antibiotic intake. In general, try to lead a healthy lifestyle and not get sick. To prevent various gynecological diseases, you can resort to the help of special dietary supplements.

Reviews

For prostatitis, it relieves swelling no worse than smartprost. The pain goes away in a matter of days. But in terms of money, you still need to calculate what is more profitable, of course.

Trichomonas colpitis is an infectious inflammation of the mucous membranes of the vagina and urinary tract. The course of treatment is prescribed various drugs, including Wobenzym, which is often used to improve the body’s immune response, for greater treatment effectiveness, to reduce side effects from antibiotics and for other indications. Treatment should be carried out under the supervision and instructions of a gynecologist, who determines the treatment tactics and the drugs used.

Hello, can you tell me whether the drug can be used for trichomonas colpitis?

I drank it myself for diseases (viral and gynecological) as an additional supplement. course to antibiotics. The doctor ordered it that way. I took all the medications only according to the instructions, and Wobenzym always helped. I had no side effects. I didn’t feel sick and there were no problems with the gastrointestinal tract. I think this is because I strictly followed the instructions. I can recommend this drug because it has helped me personally.

I took the course for six months after surgery to remove an ovarian cyst. At first I drank it together with antibiotics, to neutralize the consequences, and at the same time as a prophylaxis against adhesions, and then separately, just to strengthen the whole body. The recovery was quick and easy, and the cysts did not appear again. I think Wobenzym helped.

I was prescribed Wobenzym after a diagnostic curettage, just so that the endometrium would recover better, the doctor said that Wobenzym speeds up the processes. Thin endometrium is of course not very critical, but the egg will be implanted there, so it’s better to restore it to be on the safe side

She treated acute cestitis with cranberry juice, conephron and Wobenzym in combination. Then after the main treatment I took Wobenzym for 2 weeks so that there would be no relapse. Everything together helped.

We found uterine fibroids. I was very afraid that I would have to remove it surgically. The doctor said that it is not big, you can try to remove it with medication. I took Wobenzym for 2 months and was no longer present at the repeat ultrasound. My joy knew no bounds.

The gynecologist prescribed this drug a month ago. I conscientiously drank it every day. Now according to the tests everything is fine. My diagnosis was cervicitis.

I have cysts on the ovaries, and there is some kind of liquid in the tube. Three months ago they removed a cyst from the left ovary, and now it’s on the right again, I don’t know what to do. I am 36 years old, I have never been pregnant, we really want to, but it doesn’t work out. The ovaries have already been operated on three times, a cyst appears on the left or on the right

300 units chymotrypsin (and pancreatin presented in units (U) of the European Pharmacopoeia, and the remaining ingredients in units (U) of the International Pharmaceutical Federation).

Additional ingredients: stearic acid, lactose, talc, corn starch, purified water, magnesium stearate, colloidal silicon dioxide.

Shell composition: povidone, shellac, sucrose, methyl methacrylate-methacrylic acid copolymer, vanillin, talc, white clay, titanium dioxide, macrogol 6000, carnauba wax, triethyl citrate, bleached wax, dyes (crimson 4R and yellow-orange S).

Release form

Wobenzym is produced in the form of coated tablets of 40 or 200 pieces in packs and 800 pieces in high-density polyethylene bottles.

Pharmacological action

Immunomodulatory, fibrinolytic, antiplatelet, anti-inflammatory, decongestant.

Pharmacodynamics and pharmacokinetics

According to Medical Wikipedia (MedViki), the drug Wobenzym is a complex of highly active animals And vegetable (enzymes ). Data enzymes carefully selected, optimally combined and included in Wobenzym tablets, which gives them a fairly wide range of clinical applications.

Taking Wobenzym has a positive effect on the course of inflammatory process , reduces pathological symptoms immunocomplex And reactions , has a positive effect on immunological reactivity human body. Under the influence of the active ingredients of drugs, the number circulating in the immune complexes and their membrane deposits are removed from the tissues. The drug activates and corrects functionality natural killer cells ( ) And monocyte-macrophages , stimulates cellular activity, cytotoxic T lymphocytes And antitumor , for which the medicine Wobenzym is often prescribed as .

Treatment with Wobenzym reduces interstitial tissue infiltration plasma cells , increases deposit elimination fibrin And protein detritus from the inflamed area, accelerates the lysis of metabolic and dying tissue structures, reduces swelling , accelerates resorption , and also normalizes the permeability of vascular walls.

The use of the drug leads to a decrease in the content thromboxane , decrease platelet aggregation , stabilizing the adhesion of blood cells, increasing plasticity and their ability to change their own shape, normalizing the number and reducing total number their activated fractions, regulation blood viscosity and a decrease in the total amount microaggregates . These effects improve rheological blood parameters and her microcirculation , which ensures the normal supply of tissues and organs of the human body with nutrients and oxygen.

Wobenzym reduces replication endogenous , normalizes exchange lipids , increases concentrations HDL , reduces the content of atherogenic lipoproteins and improves absorption polyunsaturated fatty acids .

The appointment of Wobenzym enhances the effectiveness of the treatment antibiotic therapy by increasing the level funds in the focus of inflammation and their plasma concentrations, triggers the process of nonspecific defense of the body (production ), thereby exhibiting antimicrobial and antiviral effects, and also eliminates symptoms. The drug also reduces the severity of side effects that occur when taking hormonal medicines (including hypercoagulability ).

When taken orally, due to resorption dimer molecules , the active ingredients of Wobenzym are absorbed from the small intestine with the formation of protein complexes and further entry into the vascular bed. Circulating through the systemic bloodstream, enzymes fall into zones of pathological processes, where their cumulation occurs.

Indications for use of Wobenzym

The abstract for Wobenzym positions it as a means for use in combination with other drugs used for the treatment of certain pathologies, as an addition to the main treatment. Indications for the use of the drug cover many areas of medicine and recommend its use in the following cases.

In angiology:

• lymphatic;
• endarteritis ;
• postthrombophlebitic disease;
• arterial obliterator of the legs ;
• recurrent phlebitis (prevention).

In gynecology:

• miscarriage (relative to the II and III trimester);
• salpingo-oophoritis;
• vulvovaginitis ;
• reducing the severity and frequency of negative events during hormone replacement therapy;

In gastroenterology:

• (dysbiosis);
• chronic inflammatory pathologies of the gastrointestinal tract;

In dermatology:

• (acne );
• itchy dermatoses.

In neurology:

• chronic cerebral circulatory disorders;

In cardiology:

• in the subacute stage;
• voltage .

In nephrology:

In otorhinolaryngology:

In ophthalmology:

• uveitis;
• hemophthalmos;
• ophthalmic surgery and prevention of postoperative complications.

In oncology:

• and (to improve tolerability);
• reducing the risk of secondary infections.

In pulmonology:

• pneumonia;

In dentistry:

• diseases of the oral cavity of an infectious-inflammatory nature.

In rheumatology:

• of various etiologies.

In urology:

• cystopyelitis.

In traumatology:

• inflammatory processes of soft tissues;
• various ;
• post-traumatic manifestations chronic;
• sports injuries.

In pediatrics:

• pathologies of the respiratory tract of infectious and inflammatory origin;
• postoperative complications ( , insufficient wound healing, local swelling And suppuration ).

In surgery:

• lymphatic And post-traumatic edema ;
• postoperative complications ( , , inflammation ).

In endocrinology:

• And angiopathy (diabetic);
• autoimmune .

Additionally, indications for Wobenzym include the prevention of the following conditions:

• and adaptation;
• microcirculation disorders ;
• post-stress disorders;
• vascular accidents ;
• negative phenomena during ;
• viral infections or their subsequent complications;
• violations dysbiotic character at antibiotic therapy .

Contraindications

Before taking Wobenzym, you should familiarize yourself with the contraindications for its use, for which below are the conditions in which treatment with Wobenzym is absolutely prohibited:

• any pathologies that occur with an increased risk of possibility ;
• age up to 5 years;
• personal hypersensitivity to active and/or additional components of drugs;
• carrying out .

Side effects

Wobenzym therapy in most cases is tolerated without negative effects during treatment and without negative consequences after its completion. Also, so far there has been no evidence of side effects of the drug, addiction to him or formation withdrawal syndrome , even in the case of long-term therapy using high dosages.

In isolated cases, the occurrence of , as well as minor deviations in smell And stool consistency , which are leveled by reducing the dose of the drug or disappear after discontinuation of treatment.

Before prescribing Wobenzym, the patient must be warned that if he experiences any adverse reactions associated with taking the drug, his responsibility is to immediately stop therapy and further consult a doctor.

Wobenzym tablets, instructions for use

As a rule, the dosage regimen, as well as the duration of treatment, is determined individually, taking into account the disease itself, its severity, as well as all internal and external factors affecting the patient’s condition.

For adult patients, the range of single doses of the drug, depending on the pathology, its severity and activity, is 3-10 tablets with a mandatory dose of three times a day. Usually, during the first three days of therapy, they resort to taking 3 tablets three times every 24 hours. The further number of tablets taken at one time may vary, while the frequency of their intake per day in all cases remains unchanged (3 times every 24 hours).

At moderate painful conditions Prescribe 5-7 tablets three times a day for 14 days. In the future, they switch to taking 3-5 tablets with the same frequency of administration. General course treatment - approximately 30 days.

At severe painful conditions Prescribe 7-10 tablets three times a day for 14-21 days. Subsequently, the dosage is reduced to 5 tablets with the same frequency of administration. The general course of therapy is 2-3 months.

At chronic pathologies Wobenzym tablets are recommended to be taken according to indications and observed symptoms, in courses from 3 to 6 months.

To potentiate the effectiveness of the carried out antibiotic therapy and prevention of formation dysbacteriosis It is recommended to take 5 tablets three times a day throughout the entire course of use. For the purpose of treating dysbacteriosis that arose after antibiotic therapy, Prescribe 3 tablets three times every 24 hours for 14 days.

Taking into account some similarity in the composition of drugs and the distribution of their effects on the human body, we can distinguish two analogue drugs - Wobe-mugos E And .

The price of Wobenzym analogues (40 tablets) (using the example of these two drugs that are closest in action) is slightly higher than Phlogenzyma – 950 rubles and much higher for Wobe-mugos E – 2900 rubles, for the same number of tablets.

For children

Wobenzym can be prescribed to children who have reached the age of 5 years. At the age of 5-12 years, the dosage of the drug is calculated per kilogram of weight (1 tablet per 6 kilograms).

With alcohol

It should be noted right away that in case of any pathology, taking any medications, and even against the background of complete health, alcohol, especially in large quantities, cannot benefit the human body. When considering the compatibility of Wobenzym treatment with the intake of alcoholic beverages, one should also take into account the fact that this drug itself is prescribed quite rarely, but is mainly part of the complex treatment of certain diseases, which indicates the variety of possible effects of complex therapy on the body as a whole. and on its individual organs and systems. For example, when used in combination with antibiotics , antiviral drugs , chemotherapy Drinking alcohol is strictly prohibited, and even with other combinations of drugs, its use is undesirable and in best case scenario may lead to decrease in efficiency therapy, and at worst cause various severe complications . Another area of ​​application of the drug is treatment withdrawal syndrome and in this case, Wobenzym and alcohol are compatible in the same way as the very concepts of benefit and harm.

Wobenzym during pregnancy and lactation

The list of contraindications for the use of Wobenzym does not include: , so and . Moreover, during pregnancy, women are even recommended to take it for prevention of miscarriage, starting from the second trimester, where the effect of the drug receives positive reviews. During pregnancy, the calculation of the dosage and duration of taking the tablets is determined individually, taking into account general condition the expectant mother, fetal health indicators and the course of the pregnancy itself.

Reviews of Wobenzyme

Reviews about Wobenzyme on forums, as well as reviews from doctors about Wobenzyme, are quite contradictory and often lead to serious disputes among specialists and patients about the effectiveness, usefulness and safety of using this drug. The opinions of many doctors and people who have ever taken this drug differ radically on this matter, and when some claim that for them complex treatment with the inclusion of Wobenzym was much more effective and safer than without it, others immediately find many arguments against and declare the complete uselessness of this drug.

For example, some nutritionists advise taking Wobenzym for weight loss in combination with exercise physical education and explain this by the ability of the drug to normalization of the function of the gastrointestinal tract and them microflora . Some patients who have undergone this course of diet therapy remain satisfied with its results and leave positive reviews about Wobenzym. The other part, which does not notice any special changes in body weight, naturally attributes the negative result to Wobenzym.

Reviews of the drug in gynecology for ; at mastopathy , endometritis , vulvovaginitis , gestosis , cervicia ; diseases of sexual etiology ( chlamydia , mycoplasmosis , ureaplasmosis ), as well as reviews of Wobenzyme at pregnancy mostly positive, but even here there are those who see in this only a coincidence of circumstances and the effect of other medications taken at the same time.

In the current situation, it is not possible to draw any definite conclusions and therefore we can only advise you to rely on the opinion of your attending physician, especially if you trust him not only as a good specialist, but also as simply a decent person.

Wobenzyma price, where to buy

The price of Wobenzym in Russian pharmacies, due to its considerable cost, does not differ much depending on the region and therefore you can buy Wobenzym in Moscow for about the same as it costs in St. Petersburg, for example, at the Ozerki pharmacy.

The average price of 40 tablets is 450 rubles; 200 tablets – 1900 rubles; 800 tablets – 6500 rubles. The price of 100 Wobenzym tablets, when purchased “by weight” from a package of 800 pieces, is 900-1000 rubles.

Wobenzym can be bought in Kyiv on average for: No. 40 – 200 hryvnia; No. 200 – 900 hryvnia; No. 800 – 3000 hryvnia.

• Online pharmacies in Russia Russia
• Online pharmacies in Ukraine Ukraine
• Online pharmacies in Kazakhstan Kazakhstan

ZdravCity

Wobenzym tab. p.o n200Mucos Emulsions GmbH

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Wobenzym tab. p.o n800Mucos Emulsions GmbH

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Education: Graduated from Vinnitsa National Medical University named after. N.I. Pirogova, Faculty of Pharmacy, higher education pharmaceutical education– specialty “Pharmacist”.

Experience: Work in the pharmacy chains "Konex" and "Bios-Media" with the specialty "Pharmacist". Work as a Pharmacist in the Avicenna pharmacy chain in the city of Vinnitsa.

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Reviews

I tolerate antibiotics very poorly; stomatitis on the mucous membranes usually increases. That is, you get sick and you can’t even put anything in your mouth, it’s all sores and it hurts. The doctor prescribed Wobenzym for better acceptance of the antibiotic. Indeed, there was no stomatitis, she tolerated the medications well and recovered quite quickly. Now I will know if I suddenly have to take antibiotics again.

My husband suffered for a long time with chronic prostatitis, different doctors gave different treatments. But only with the introduction of Wobenzym into treatment was it possible to cure this chronic condition. The course is expensive and lengthy, but the man’s health and family well-being are worth the money.

I was treated for endometriosis for a long time; doctors prescribed one treatment or another. The effect appeared when a course of Wobenzym was prescribed. The doctor said that it kind of stimulates the treatment, helps and speeds it up. The drug is natural, so there was no addiction, although it took a long time to take.

Before (and after) small gynecological surgery I started taking Wobenzym to prevent the appearance of adhesions. And then I also drank it, as it helps the body recover faster. The gynecologist was pleased with his result.

Wobenzym was prescribed to me after a gynecological operation so that the tissue would be restored better and adhesions would not form; the enzymatic composition was very well selected. The drug helped - everything healed quickly and without consequences

I took it 2 times, very satisfied. The first time I was discharged after surgery so that adhesions would not form, the second time I was treated for thrush, the doctor recommended Wobenzym to enhance the effect of antifungal drugs and boost immunity so that it would not recur.

We couldn't conceive a child for 2 years. We were already thinking about going for IVF. And then I went to another gynecologist and it turned out that I simply had adhesions in my tubes after inflammation. The doctor immediately prescribed Wobenzym for the resorption of pathological tissues and prescribed a course of electrophoresis with enzymes. And already 3 months after treatment I became pregnant!

Wobenzym was taken for two months after giving birth to speed up the body's recovery process. I really recovered quickly; after a month at the examination they said that all the stitches from the tears had almost completely healed. Maybe, of course, it’s just my natural feature that tissues are restored so quickly and wounds heal (although I haven’t noticed this before), but I can say for sure that Wobenzym has strengthened my immunity. I gave birth in October, now it’s June, and during all this time I have never caught a cold, I haven’t even had a slight runny nose, can you imagine?! Although earlier the snot flowed immediately as soon as the breeze blew. So it definitely works as an immunostimulant.

This drug was prescribed by a gynecologist after laparoscopy. She explained to me that Wobenzym inflammatory processes good remedy and will boost your immunity at the same time. I drank it for one month. Luckily for me, no new adhesions formed. Yes, and the blood test showed good results- the inflammation went away quickly.

Wobenzym is a universal drug. I drink it when I'm sick viral diseases- to boost immunity. I also parted with thrush thanks to him. There have been no thrush for several years now, but before it used to constantly come out and give me a bunch of discomfort and discomfort. I think women who have experienced this will understand me. In general, I recommend it to all representatives of the fair sex.

Wobenzym is a godsend for me. Its enzymes improve the functioning of the entire body. I periodically take a course of Wobenzym and feel great. The first time it was prescribed to me by a gynecologist for inflammation of the appendages. When I started taking it, the pain in the lower abdomen immediately went away, apparently it also has an analgesic effect.

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Instructions for use:

Wobenzym is a drug with anti-edema, antiplatelet, anti-inflammatory, immunomodulatory and fibrinolytic effects.

Release form and composition

Wobenzym is produced in the form of enteric-coated tablets, red-orange in color, biconvex, round, with a characteristic odor and smooth surface (20 pcs. in blisters, 2 or 10 blisters per cardboard box; 800 pcs. in polyethylene bottles).

1 tablet contains the following active ingredients:

• Papain – 90 units Federation International Pharmaceutical (IU (FIP));
• Pancreatin – 345 proteolytic units of the European Pharmacopoeia (prot. UN EF);
• Bromelain – 225 units (FIP);
• Rutoside trihydrate – 50 mg;
• Lipase – 34 units (FIP);
• Trypsin – 360 units (FIP);
• Chymotrypsin – 300 units (FIP);
• Amylase – 50 units (FIP).

Excipients included in the drug: resin, magnesium stearate, lactose monohydrate, macrogol 6000, corn starch, purified water, stearic acid, highly dispersed silicon dioxide, talc, sucrose, calcium carbonate, methacrylic acid and methyl methacrylate copolymer (1:1), titanium dioxide, povidone, triethyl citrate, vanillin, bleached and carnauba wax, white, yellow-orange S (E110) and crimson 4 R (E124) dyes.

Indications for use

Wobenzym is prescribed in combination with other drugs for the treatment of the following diseases:

• Gastroenterology – hepatitis, chronic inflammatory diseases gastrointestinal tract, dysbiosis;
• Angiology – lymphatic edema, post-thrombophlebitis disease, thrombophlebitis, prevention of recurrent phlebitis, endarteritis and obliterating atherosclerosis of the arteries of the lower extremities;
• Dermatology – acne, atopic dermatitis, itchy dermatoses;
• Gynecology – chronic and acute infectious and inflammatory diseases of the genitals (cervicitis, salpingoophoritis, vulvovaginitis, endometritis), complex therapy for miscarriage of the 2nd-3rd trimesters, mastopathy, gestosis, reduction in the severity and frequency of undesirable effects of hormone replacement therapy, sexually transmitted infections; in combination with antibiotics: ureaplasmosis, chlamydia, mycoplasmosis;
• Neurology – chronic cerebrovascular accidents, multiple sclerosis;
• Cardiology – subacute stage of myocardial infarction, exertional angina;
• Oncology – improving tolerability during chemotherapy and radiation therapy and reducing the risk of associated infectious complications;
• Nephrology – pyelonephritis, glomerulonephritis (simultaneously with antibiotics);
• Otorhinolaryngology – sinusitis, otitis, sinusitis, laryngitis (simultaneously with antibiotics);
• Pediatrics – atopic dermatitis, infectious and inflammatory diseases of the respiratory tract (pneumonia, inflammation of the upper and lower respiratory tract), treatment and prevention of postoperative complications (poor wound healing, suppuration and local edema, adhesive disease);
• Ophthalmology – glaucoma, iridocyclitis, uveitis, diabetic retinopathy, hemophthalmos, prevention of complications after operations, ophthalmic surgery;
• Rheumatology – reactive arthritis, rheumatoid arthritis, juvenile rheumatoid arthritis, osteoarthritis;
• Pulmonology – tuberculosis, tracheobronchitis, bronchitis, obstructive bronchitis, pneumonia;
• Urology – prostatitis, cystopyelitis, cystitis, sexually transmitted infections (simultaneously with antibiotics);
• Traumatology – inflammation of soft tissues, chronic post-traumatic processes, injuries, injuries in sports medicine;
• Endocrinology – diabetic retinopathy, diabetic angiopathy, autoimmune thyroiditis;
• Dentistry – infectious and inflammatory diseases of the oral cavity;
• Surgery – prevention of postoperative complications (edema, thrombosis, inflammation), lymphatic and post-traumatic edema.

For preventive purposes, Wobenzym is prescribed according to the following indications:

• Vascular accidents, microcirculation disorders;
• Post-stress disorders, failure of acclimatization and adaptation;
• Side effects of hormone replacement therapy;
• Development of viral infections and their complications;
• Dysbiotic disorders when using antibiotic drugs.

Contraindications

• Diseases associated with an increased likelihood of bleeding (thrombocytopenia, hemophilia);
• Carrying out hemodialysis;
• Children under 5 years of age;
• Hypersensitivity to the components of the drug.

Directions for use and dosage

Wobenzym is taken orally, at least 30 minutes before meals or 2 hours after meals, with water (150 ml). You should not bite the tablets.

Typically, adults are prescribed Wobenzym in the minimum therapeutic dose - 3 times a day, 3 tablets for a course of 2-5 weeks.

With average disease activity, it is recommended to take 5 tablets 3 times a day, the course duration is 14-28 days. If improvement is observed, after 7 days from the start of therapy, the single dose can be reduced to 3 tablets. To achieve a long-term effect, it is recommended to carry out repeated therapeutic courses for 1.5-2 months after a 14-day break.

With high disease activity, the drug is taken 3 times a day, 7 tablets for a course of 21 days. If there is improvement, after a week from the start of taking Wobenzym, the single dose is reduced to 3 tablets and the course duration is increased to 1.5 months.

For long-term chronic diseases The drug is taken according to indications in courses of 3-6 months with breaks of 14-28 days.

During planned operations, Wobenzym is used to prevent complications (adhesive disease, keloid scar, inflammation). The drug is started to be taken before surgery 3 times a day, 3 tablets for a course of 5 days. Therapy should be completed 3 days before surgery.

To increase the effectiveness of antibiotic drugs and reduce the severity of side effects, as well as to prevent dysbiosis, Wobenzym is prescribed for the entire course of antibiotic therapy 3 times a day, 5 tablets. To restore the intestinal microflora after completing a course of antibiotic treatment, it is recommended to take the drug for 7-14 days, 3 tablets 3 times a day.

As a “cover” therapy during chemotherapy and radiation therapy to improve tolerability, prevent infectious complications and improve quality of life, Wobenzym is prescribed 5 tablets 3 times a day until the course of treatment is completed. In the future, to restore immunity, the drug is taken for 21 days, 3 times a day, 3 tablets.

For preventive purposes, to increase resistance to diseases, the threshold of adaptation and reduce the risk of vascular accidents and diseases, Wobenzym is recommended to be taken in a course of 3-6 weeks, 2-3 tablets 3 times a day. The course can be repeated 2-3 times a year.

The drug is approved for children from 5 years of age. Wobenzym is prescribed at the rate of 1 tablet per 6 kg of child’s weight, the frequency of administration is 2 times a day. The duration of the course is determined by the diagnosis and condition of the child and can vary from 2 to 5 weeks. Children over 12 years of age are prescribed the drug in the same way as adults.

When treating infectious diseases in children, Wobenzym is recommended to be taken simultaneously with antibiotics to increase their effectiveness during the entire course of therapy in a dosage determined according to the weight and age of the child.

To increase immunity and restore the intestinal ecology after the end of etiotropic and antibacterial anti-infective treatment, the drug is taken 2 times a day, 1 tablet. For children over 12 years of age, the single dosage should be increased to 2 tablets. Recommended course – 7-21 days. The duration of use of the drug is determined by the doctor.

For recurrent inflammatory diseases in long-term and frequently ill children, Wobenzym is recommended to be taken for 3-6 weeks, 2 times a day, 2 tablets or in dosages calculated based on the weight and age of the child. To achieve improvement in condition and stable remission in long-term and frequently ill children, it is recommended to conduct several repeated courses per year for 3-6 weeks with a break of 7-14 days. The duration of use of the drug and dosage are determined by the doctor.

Side effects

Wobenzym is usually well tolerated, provided that the basic recommendations for its use are followed: tablets should not be crushed, and it is also necessary to observe intervals between taking the drug and food (30 minutes before or 2 hours after meals).

In some cases, during therapy, the development of such side effects, such as: minor changes in the smell and consistency of feces, vomiting, nausea, heaviness in the stomach, diarrhea, skin rashes in the form of urticaria, allergies to the components included in the drug. These symptoms disappear when the dose is reduced or the drug is discontinued.

The syndrome of addiction and withdrawal was not detected even with prolonged therapy with high doses.

If adverse reactions not noted in the instructions develop, it is recommended to discontinue treatment and consult a doctor.

Special instructions

It must be taken into account that when you start taking Wobenzym, the symptoms of the disease may worsen. Treatment should not be interrupted in such cases; it is recommended to temporarily reduce the daily dose of the drug.

In infectious diseases, Wobenzym does not replace antibiotics, but increases effectiveness by increasing their concentration in microbial colonies, tissues and the site of inflammation.

The drug is not a doping and does not have a negative effect on driving a car or performing work that requires a high speed of physical and mental reactions.

Drug interactions

When Wobenzym is taken simultaneously with other drugs, cases of incompatibility have not been described.

Analogs

Analogs of Wobenzym are: Wobe-mugos E, Flogenzym.

Terms and conditions of storage

Store in a dry place, out of reach of children, at a temperature of 15-25 °C.

Shelf life – 2.5 years.