Panangin is compatible with alcohol. Is it possible to take Panangin after alcohol? Medicines, alcohol and chronic diseases

26.04.2019

"Panangin" and alcohol: compatibility, mutually exclusive effects, effects on the body when taken and possible consequences. Is it possible to combine panangin and alcohol?

Again, after yesterday's holiday, my head is cracking, I feel sick and feel completely overwhelmed. This is the “sweetness” of a hangover. And you don’t know what medicine to grab to relieve the unpleasant symptoms. One of effective means in the fight against hangover - panangin.

What is Panangin

Panangin (or asparkam) is a drug that is a source of potassium and magnesium in case of their deficiency in the body. The active ingredient of this inexpensive and very accessible medicine in tablet form at any pharmacy is potassium aspartate and magnesium aspartate. If you are prescribed the drug as part of a dropper, then the active ingredients are magnesium and potassium aspartate.

This drug performs the following functions:

  • Restores electrolyte balance,
  • Eliminates arrhythmia,
  • Regulates metabolic processes.

Panangin is usually prescribed in the following cases:

  1. lack of potassium and magnesium,
  2. chronic circulatory disorder,
  3. shock states arising for various reasons,
  4. coronary heart disease,
  5. heart rhythm disturbances.

It would seem – what does alcohol and a hangover have to do with it? But here's what it has to do with it.

How does panangin (asparkam) work for a hangover?

The fact is that alcohol is a strong diuretic, i.e. diuretic. This is why you often want to go to the toilet during a feast with alcohol. As a result, too much magnesium and potassium are excreted from the body in urine.

Thus, the next morning with a hangover, a severe deficiency of potassium and magnesium occurs in the body, especially the first element. At the same time, a lack of magnesium leads to saturation of the blood with calcium, which is washed out of the bones in excess. A lack of calcium in the skeletal system threatens such a serious disease as osteoporosis.

At the same time, an excess of calcium in the human body causes pronounced symptoms of a hangover, such as:

  • nervous excitability,
  • chills,
  • muscle weakness,
  • heart problems.

Thus, panangin (asparkam), replenishing the lack of these two in the body important elements, leads to quick elimination listed hangover symptoms.

By the way, this drug is an integral part of a home first aid kit for emergency drug treatment.

How to take Panangin for a hangover

To relieve hangover symptoms, it is enough to take 1-2 tablets of Panangin. However, in most cases, when the consequences of excessive alcohol intake are not very pronounced, it is better to get by with brine and other folk remedies, because Panangin has a number of contraindications for use, namely:

  • illnesses cardiovascular system,
  • renal failure (acute and chronic),
  • excess potassium and magnesium in the body,
  • myasthenia gravis in severe forms.

In addition, the drug itself has such side effects such as: nausea, vomiting, headache, abdominal pain, etc.

Panangin is a source of potassium and magnesium, which are involved in metabolic processes involved in the synthesis of DNA and proteins required for cell growth. But will this drug be beneficial if combined with alcohol to treat a hangover?

Panangin and alcohol

Panangin is a drug in tablets and ampoules for injections from the group of mineral-containing, antiarrhythmic combination drugs. Panangin contains potassium aspartate and magnesium aspartate.

Panangin supplies the body with potassium and magnesium. Due to aspartate, it participates in the utilization of endogenous ammonia, converting it into urea. Aspartate is a salt of aspartic acid, serves as a neurotransmitter - is involved in the transmission of nerve impulses.

Panangin is prescribed for patients with an increased risk of cardiovascular diseases, for persons taking diuretics, sedatives, hormonal drugs, contraceptives, for leg cramps, and high blood pressure.

Interaction

Panangin is allowed for treatment as part of complex therapy. The main purpose of the drug is to maintain the functioning of the heart muscle (myocardium). The drug is used to treat withdrawal symptoms, when alcohol is no longer present in the patient’s blood.

The drug is also used for hangovers, in combination with other medications. But the drug is not used as an independent remedy that can relieve a severe hangover.

Panangin should not be combined with alcohol. Alcohol reduces blood pressure, causes dehydration caused by the diuretic effect. In these conditions, taking Panangin is contraindicated.

Possible consequences

Contraindications for taking Panangin include dehydration and acidosis. These are precisely the conditions that occur when drinking alcohol during a hangover.

Alcohol abuse is cited as one of the main causes of acidosis. This condition is characterized by:

  • malaise;
  • nausea, vomiting;
  • increased heart rate;
  • arrhythmia;
  • shortness of breath with little physical exertion;
  • confusion;
  • shock.

This condition is caused by a shift in the acid-base balance towards acidification of the blood, and is treated by taking medications containing organic acids (succinic, citric).

It is the symptoms of acidosis that plague a hangover. Taking Panangin in a small dosage is useless, and with increased doses of the drug it will cause unpleasant side effects.

Thus, the simultaneous use of Panangin and alcohol can cause spasm of blood vessels. A particular danger is posed by uncontrolled intake and overdose of potassium and magnesium with the development of hyperkalemia and hypermagnesemia. Accordingly, the answer to the question of whether it is possible to combine is a categorical no.

Hyperkalemia

A high concentration of potassium - hyperkalemia, is characterized by arrhythmia, a change in heart rate with a decrease in heart rate (bradycardia) or an increase (tachycardia).

With an overdose of Panangin, it is possible to develop such a dangerous condition to health as ventricular fibrillation of the heart - disorganized contraction of the myocardium with a frequency of up to 300-400 beats per minute.

In this condition, blood circulation is disrupted and there is no pulsation of large arteries. With a high concentration of potassium in the blood, significantly exceeding the norm, cardiac arrest is possible.

A high concentration of potassium in the blood is dangerous due to the risk of respiratory and cardiac arrest. Hyperkalemia develops when the excretory function of the kidneys is impaired or when there is an overdose of drugs containing potassium.

During hospital treatment, potassium deficiency, which is almost always observed in those suffering from alcoholism, is eliminated by intravenous administration of potassium chloride. On the first day of treatment for withdrawal syndrome, only 50% of the required amount of this macroelement is administered due to the danger of exceeding the dosage.

And the concentration of potassium in the blood is measured every day.

Hypermagnesemia

Deviations in the concentration of magnesium in the blood cause life-threatening conditions. Taking Panangin without a doctor's prescription, without taking into account the patient's health condition, can cause an increase in the concentration of magnesium in body fluids - hypermagnesemia.

With an increased concentration of magnesium in the blood, depression of the respiratory center, disruption of heart function, and coma are possible.

Patients with alcoholism almost always have a deficiency of magnesium, which is manifested by drowsiness, weakness, convulsions, and heart rhythm disturbances. Replenish magnesium deficiency with magnesium gluconate. Panangin is used in hospitals, but as an additional agent, gluconate and magnesium oxide are often administered intravenously.

The body may have a lack of potassium with normal magnesium concentrations. Taking Panangin to replenish potassium in the blood, you can overdose on magnesium concentration. And vice versa.

We are not talking about 1-2 tablets taken for a hangover. If you take this amount of medicine for a hangover, there is no need to worry. But this mistake should not be repeated; self-prescription of any medicine without preliminary tests or a doctor’s prescription can lead to unexpected consequences.

Symptoms of hypermagnesemia

Is it possible to combine

Taking Panangin after alcohol has no practical significance. In small doses, it does not improve the patient’s condition in any way, but the drug will not cause harm in such quantities. You can take the drug in the first 2 hours after waking up at a dose of 1-2 tablets.

When increasing the dose or repeating the dose, the risk of overdose increases. It is very dangerous to take even such a seemingly harmless drug without knowing how low the concentration of potassium and magnesium is.

You cannot treat a hangover with Panangin on your own, or use it simultaneously with alcohol. The safety condition for using Panangin is to control the level of potassium and magnesium in the blood, which is impossible to do at home.

The first manifestations of a hangover can be observed within a few hours after drinking alcohol. Increasing headache, rapid heartbeat, loss of orientation in space, chills, fever, dizziness, indigestion - far from full list symptoms that characterize a person’s morning state after a successful party.

It is not surprising that a person in such a state is ready to use any available means to alleviate the unpleasant and painful symptoms of alcohol poisoning. Some are “treated” only with proven recipes traditional medicine, others rely exclusively on medicines from the home medicine cabinet. Using Asparkam for a hangover, many consider it one of the most effective drugs to restore vitality and get rid of unpleasant symptoms"morning sickness" Let's try to figure out if this is so.

How does Asparkam work?

Asparkam (aka Panangin) is a medicine intended to replenish magnesium and potassium in case of their deficiency in the human body. The drug is produced in the form of tablets and ampoules for injection. Depending on this, the main active ingredients are potassium and magnesium aspartate in the first case and magnesium and potassium aspartate in the second. According to the official annotation, the medication is recommended for patients to:

  • lack of microelements in the body;
  • coronary heart disease;
  • chronic circulatory disorders;
  • heart rhythm disturbances.

Panangin helps in short terms restore the balance of electrolytes, eliminate arrhythmia and stabilize metabolic processes in the patient’s body. This means it contributes to the rapid restoration of the patient’s vitality and his speedy recovery.

Important! When taking Asparkam, you should strictly follow your doctor's instructions and dosage. If the medicine is taken independently, you must strictly follow the instructions for the medicine. Do not abuse the tablets or exceed the recommended dosage. Dangerous complications, including death, are possible.

How to combine with alcohol

Alcohol is a strong diuretic. Consequently, it is capable of removing a significant amount of fluid from the human body in a short time. Along with urine, a person loses quite a lot minerals. Especially potassium and magnesium. This leads to disruption of metabolic processes and malfunctions of organs and systems. At the same time, the concentration of calcium in the blood increases, which is actively washed out of bone tissue. Excess calcium increases hangover symptoms, especially:

  • chills;
  • muscle weakness;
  • increase in temperature;
  • changes in blood pressure;
  • photophobia;
  • nervous excitability.

Important! By taking Panangin for a hangover, you can quickly replenish the lack of potassium and magnesium in the body, which means eliminating painful symptoms and restoring the normal functioning of vital organs. The medicine is especially effective in combination with other drugs that are used to treat alcohol poisoning.

How to take it correctly

The instructions for use included with each package of Asparkam fully describe the drug, indications for use, side effects, dosage, compatibility with other medications and contraindications. When taking the product yourself, you should read the instructions and strictly follow its instructions.

As numerous reviews indicate, it is better to drink Asparkam after cleansing the body of toxins and getting rid of nausea and vomiting. That is, after waking up you should immediately take the sorbent - Activated Carbon, Enterosgel, Zorex. After that you can have a drink green tea, mineral water still, herbal decoction, kefir or yogurt. And only then take Asparkam for a hangover. Correct dosage is 1-2 tablets depending on the severity of symptoms.

Important! If the symptoms are very mild (no nausea or vomiting, frequent urination and diarrhea), you can do without taking the drug. In case alcohol poisoning very strong and it is not possible to alleviate the symptoms within 2-3 hours - you should immediately call an ambulance. In this situation, taking Asparkam can only do harm.

Contraindications

Along with beneficial properties Panangin also has a number of contraindications for use. So, the medicine should not be used if a person has low blood pressure, excess magnesium and calcium in the body, various states of shock, chronic or acute renal failure.

Important! Uncontrolled use of the drug can even cause cardiac arrest! Therefore, before taking Asparkam, it is better to consult a doctor.

Deaths from coronary heart disease and stroke account for about 17.5 million people every year.

In 54% of cases, death occurs due to alcohol abuse.

Violation of water-electrolyte and acid-base balance causes a decrease in protein synthesis in the myocardium by 15%, the development of hypokalemia and hypomagnesemia is observed within 36-72 hours after 50 grams of ethyl alcohol.

10% drinking people the intoxication state is accompanied by extrasystole and atrial fibrillation; in 25-30% the situation is complicated by atrial and ventricular fibrillation. To restore metabolic processes, it is necessary to regulate the level of potassium and magnesium with the help of medication.

But the drug Panangin is not compatible with alcohol. Therefore, in order not to cause cardiac arrest from a hangover, it is better to choose another effective but safe remedy.

Why take Panangin: features and action


In cardiological practice, the properties of K + and Mg 2+ are widely used to treat pathologies and disorders of the functional functioning of the cardiovascular system. Vital macroelements are responsible for the processes of myocardial excitability, slowing down neural transmission and relaxing smooth muscles.

They provide energy metabolism, maintain permeability and osmotic pressure cell membrane, participate in the synthesis of proteins, fats and carbohydrates.

Since 2007, the drug known under the trade name Panangin® began to play the role of a source of magnesium and potassium. And in 2015, the manufacturer GEDEON RICHTER released a new product on the pharmaceutical market medicine with the addition of the word Forte and dietary supplement Panangin® Plus vitamin B6 to the existing name. For sale and distribution to the population, the pharmaceutical product is presented in tablet form.

Inside each white capsule with a glossy or film surface there are:

  • magnesium, potassium aspartate;
  • povidone K30;
  • corn, potato starch;
  • colloidal silicon dioxide;
  • Magnesium stearate.

Considering the original package insert, qualified reviews and the opinion of cardiologists, it is important to take Panangin during complex drug therapy, which is aimed at eliminating K and Mg deficiency in order to prevent heart failure and heart attack.

Against the background of hypokalemia and hypomagnesemia, the medication is used to treat such manifestations as arrhythmia, paroxysmal supraventricular tachycardia, atrial and ventricular extrasystole.

You can speed up the action of Panangin by prescribing transparent, with green tint liquid composition for infusions. The concentrate consists of potassium, magnesium ions, and water for injection.

To improve heart rate contractility, restore the ratio of calcium, potassium, magnesium and sodium ions, stop the development of atherosclerosis, hypertension, changes in the myocardium, arrhythmia and enhance the anti-ischemic effect, doctors recommend Panangin.

Be sure to drink it after meals. Daily norm- 1-2 tablets in the morning, lunch and evening. For intravenous injection and drip infusion, dilute the contents of 1-2 ampoules with 5% glucose. Repeat administration is allowed every 4-6 hours.

There is no information that alcohol and Panangin cannot be combined.

Among the contraindications were atrioventricular block II, III degrees, sensitivity to sorbitol and fructose, first trimester of pregnancy, Addison's disease, renal and adrenal insufficiency, cardiogenic shock, arterial hypotension, myasthenia gravis, excess magnesium, potassium.

Side effects include skin flushing, dry mouth, fatigue, dyspeptic disorders, decreased heart rate and even cardiac arrest.

Is it possible to combine alcohol and Panangin?


Due to its physicochemical properties and ability to easily interact with liquid media ethyl alcohol interferes with everything metabolic processes, has a strong toxic effect on the body. In every 4 cases, the cardiovascular system suffers from ethanol.

If Panangin is consumed simultaneously with alcohol, cardiomyocytes begin to be damaged.

Under the influence of alcohol, the activity of sodium excretion increases, which causes the need for oxygen. The transport of potassium into the extracellular space is inhibited.

The interaction of alcohol and Panangin has a cardiodepressive effect. Penetrating into myocardial tissue, ethanol reacts with fatty acids such as oleic, palmitic, linoleic, forming esters.

The high rate of synthesis of toxic compounds activates lipid oxidation and promotes the deposition of amino acids in the tissues of the heart. As a result, heart rate and breathing are suppressed.

About 90% of the breakdown products of acetaldehyde are converted into acetate.

The breakdown of salts increases the load on the liver and energy costs. The oxidation of carbohydrates and fatty acids stops, the level of ammonia in the blood increases, which in high concentrations impedes the excretory function of the kidneys.

The combination of alcoholic beverages and Panangin leads to a retention of uric acid in the body, urolithiasis, renal failure.

As part of the plasma, acetaldehyde enters the bloodstream from the biliary system, creating stable connections with the vascular endothelium, structural and functional proteins, and blood cells. Reaching nervous system, ethanol causes a decrease in calcium in parts of the brain and stimulates the release of large amounts of hormones by the adrenal glands.

The consequence of pathological changes in the endocrine system can be Addison's disease, in which it is strictly forbidden to drink Panangin or combine it with alcohol.

Water-electrolyte imbalance occurs in 30-40% of people diagnosed with alcoholism.

Daily drinking has a negative effect on the secretion of antidiuretic hormone. An increase in the volume of urine excreted stimulates the activity of the renin-angiotensin system, which has direct relation to the occurrence of hypertension, difficulty in the absorption of potassium and magnesium, and acid-base imbalance.

Panangin for hangover


Along with the lack of nutrients that leave the body with feces, vomiting and urine, increasing metabolic disorders, against the background of severe myocardial dystrophy and respiratory failure during a hangover, it is better not to even think about taking Panangin.

Characteristic signs of a large hangover are intracellular acidosis, compensatory movement of sodium and hydrogen ions into the cell, excessive activity of the central nervous system and convulsions. If you take Panangin with a hangover, it is possible that the volume of circulating blood and the contractile function of the heart will decrease.

The formation of multiple foci of excitation in parts of the brain and disruption of metabolic energy processes increases the risk of toxic myocardial dystrophy, fibrillation, extrasystole, and arrhythmia.

This is accompanied by the so-called withdrawal or a slowdown in urine formation, or a sharp increase in diuresis with the release of nitrogenous compounds, high acetate production, and symptoms of uremic intoxication.

Despite all the serious consequences, cardiologists, at their own peril and risk, prescribe Panangin for a hangover if the patient has pronounced post-intoxication arterial hypertension.

What could be the consequences of taking it?


Only a qualified specialist, based on the results obtained through laboratory and hardware diagnostics, has the right to decide whether Panangin and alcohol are compatible.

U healthy person potassium is part of cells and tissues, plays an important role in ionic balance, conduction of nerve impulses in muscles, normalization of osmotic pressure, dilates blood vessels internal organs and narrows peripheral capillaries, maintains water-salt balance.

The consequence of consuming Panangin after alcohol or with a hangover can be hyperkalemia.

It is associated with the entry of a high concentration of K + into the bloodstream and the body’s inability to absorb the macronutrient. It occurs due to deterioration of the urinary system, decreased sensitivity of the receptors of the distal tubules of the kidneys, and manifests itself in the case of intracellular acidosis, ischemia, hypoxia, and damage to cell membranes.

In patients, it is accompanied by muscle weakness, tachycardia, bradycardia and arrhythmia.

Hypermagnesemia– a complication that appears after the interaction of Panangin and alcoholic beverages.

An increase in magnesium in the blood serum occurs due to the redistribution of the macroelement from cells into the intercellular fluid, impaired absorption of the intestine, dyspeptic disorders, inhibition of the activity of neurons in the respiratory center, chronic acidosis, arterial hypotension, and renal failure.

In the absence of timely adequate treatment, hyperkalemia and hypermagnesemia result in cardiac arrest and fatal. Therefore, before starting use, you need to undergo consultation and approval of the treating doctor.

Very often, when taking medications, people ask the question: “Can they be combined with alcoholic beverages?” To figure out whether compatibility between alcohol and a drug is possible, you need to find out what the drug is and how it acts on the body.

Effect of the drug

Panangin refers to medicines that have an effect on metabolic processes in the body. The medicine contains minerals - potassium and magnesium. Potassium maintains magnesium concentrations in the required amount, regulates blood pressure and helps obtain energy from glucose. Magnesium is involved in protein synthesis and glucose breakdown. Sufficient quantity The mineral promotes the absorption of vitamins C, B1 and B6. Magnesium relaxes the muscles of the heart and dilates the arteries.

The drug is prescribed for potassium and magnesium deficiency, as well as to combat heart rhythms. Taking Panangin allows you to increase the amount of microelements in the human body and normalize the functioning of the heart and blood vessels. The medicine is prescribed by a doctor for chronic heart diseases, complex treatment after myocardial infarction. Panangin is prescribed for the treatment of blood vessels. However, in this case, taking vitamins C and P will be much more effective, so they can replace taking medication.

Contraindications for use

It is necessary to be treated with the drug with caution, since there are diseases that are a contraindication for use. The drug has high degree absorption and excreted from the body through the work of the kidneys. There are the following restrictions on taking the drug:

  • renal failure;
  • severe form of myasthenia;
  • extreme degree of left ventricular failure;
  • individual intolerance;
  • hyperkalemia;
  • hypermagnesemia;
  • insufficient water content in the body and other diseases.

In addition to contraindications, the drug also has side effects - vomiting, redness of the skin, nausea, convulsions, difficulty breathing, decreased blood pressure, arrhythmia and bradycardia.

Compatibility of Panangin and alcohol

All experts say that it is strictly forbidden to take Panangin and alcohol at the same time. The compatibility of the drug and alcoholic beverages is poor. There are several reasons for this:

  1. Drinking strong drinks has a lowering effect on blood pressure.
  2. When drinking alcoholic beverages, blood vessels dilate.
  3. Alcohol in large doses and the simultaneous use of Panangin disrupts water-salt metabolism, which leads to the body losing water and trace elements (calcium, magnesium, phosphorus and potassium).
  4. In addition, the drug is prescribed to people with cardiovascular disease, which in itself is a contraindication for drinking alcohol.

By taking Panangin and alcohol, you can be sure that the following consequences will occur for the body:

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  1. sharp and sudden narrowing of the arteries (angina);
  2. difficulty breathing, and sometimes stopping.

Panangin should not be combined with alcohol during the treatment period. Of course, in small doses, weak alcoholic drinks cannot harm a person, but they will worsen the course of the disease and treatment will not bring results.

The use of Panangin for the treatment of post-toxication syndrome

Post-intoxication (hangover) syndrome is a condition associated with alcohol poisoning. There is an opinion that Panangin is prescribed for the treatment of hangover syndrome, when, due to chronic alcoholism, a break from alcohol has occurred. The drug can indeed be prescribed during the period of recovery from a long binge. The fact is that during this period a person experiences dehydration and loss of important microelements and salts. Therefore, Panangin is prescribed in the following cases:

  • to normalize water and salts received and removed from the body;
  • for the treatment of heart disease (in remission).

Infusion therapy for acute alcohol poisoning

Promotes the removal of alcohol from the body by intravenous administration of 10 ml of Panangin solution, 5 ml of 5% solution of vitamins B 6, B 1 and C in combination with a solution of sodium chloride and hemodez. Panangin helps normalize the balance of water and salts, the vitamin complex normalizes metabolism and promotes detoxification. The effective action of the dropper is due to the fact that the medicinal substances are delivered directly into the blood.

Similar treatments also exist reverse side. With a severe hangover, a person’s blood thickens, which is associated with dehydration. This reaction leads to an increase in potassium in the body. Taking Panangin will lead to an overdose of potassium, which will pose a threat to human life - due to the heavy load, the heart may stop. The administration of Panangin in the form of a dropper leads to hypotension (a sharp decrease in pressure).

That is why taking Panangin during a hangover is enough controversial issue. Before prescribing a medicine, the doctor must carefully examine the patient's condition. The drug can be prescribed during this period if the person has completely given up drinking alcohol. The drug is taken to normalize heart function and will not cause an overdose.

Panangin (during the treatment period) should not be combined with alcohol, this can lead to a deterioration in well-being and the person will not receive the expected result from the treatment.

Panangin is available in tablets and ampoules and contains microelements: potassium and magnesium, which have a positive effect on the functioning of the cardiovascular system. The drug is taken in long courses and does not combine well with alcohol.

How does the drug interact with alcohol?

Panangin improves the conduction of impulses in the myocardium. The drug is prescribed for:

  • arrhythmias of atrial or ventricular origin;
  • myocardial infarction and rehabilitation in the post-infarction period;
  • heart failure.

The effect of the product on the body occurs at the cellular level. Action potentials and the functioning of the sodium-potassium pump are normalized. Excitation along the nerve bundles of the heart occurs in a timely manner, and there are no interruptions in the heart rhythm.

The medicine does not affect the functioning of the liver, and also does not put a strong burden on the kidneys. Therefore, the unwanted interaction of alcohol with Panangin occurs at the level of the bloodstream. When increasing the dose of tablets, there is a risk of changes in the electrolyte balance of the blood, microelements, and acid-base balance. Under the influence of large doses of alcohol, changes occur faster, and therefore the negative effect is stronger.

The compatibility of potassium, magnesium and ethyl is low. When Panangin and alcohol are simultaneously ingested in standard doses, the effectiveness of the medicine is reduced. While drinking alcohol, the kidneys intensively excrete metabolic products and microelements (potassium, magnesium) along with urine. Therefore, the effect of the drug is lost even before its components begin to act.

Possible consequences

If the dosage of alcohol exceeds acceptable standards(and this is 20 ml of pure alcohol per day), then the simultaneous use of Panangin with alcohol will result in:

  • bronchospasm, suffocation;
  • spasm of blood vessels, which will lead to hypertensive crisis or cardiogenic shock.

IN in some cases Dyspeptic disorders are observed: nausea, vomiting. Arrhythmia develops, heart rate increases, shortness of breath appears. Dizziness and confusion are possible, as manifestations of food poisoning and intoxication of the body. Side effects are increased if the patient drinks alcohol chronically and has a history of renal failure.

Death from drinking alcohol and Panangin is possible. Its probability is no more than 0.5% of the total side effects of the drug. It increases with binge drinking, exceeding the recommended dose of medication, concomitant disorders of salt metabolism, chronic kidney disease, Addison's disease.

Hyperkalemia

Hyperkalemia develops when there is a loss of blood plasma and an accumulation of potassium in the blood of more than 5.5 mmol per liter. The condition is dangerous due to cardiac arrhythmias and cardiac arrest during the contraction phase. Hyperkalemia can occur with an overdose of Panangin, as well as in the case of taking drugs during a binge.

This is explained by the fact that an overdose of alcohol causes not only intoxication of the body, but also a state of dehydration (dehydration) of cells. Liquid is removed from the body due to the action of the kidneys, as a result of which the blood acquires an acidic reaction and a thick consistency. There is a lot of potassium in relation to the reduced amount of plasma (liquid component) of the blood.

This cause of mortality from taking Panangin together with alcohol accounts for 80% of cases, and to relieve ventricular paroxysm with hyperkalemia it is necessary ambulance and a defibrillator.

Hypermagnesemia

Hypermagnesemia is a condition in which the amount of magnesium in the blood increases to more than 1.2 mmol/l. The condition is dangerous due to paralysis of muscles, nerve structures, and respiratory arrest. High level magnesium causes coma, cardiac arrest in diastole (during relaxation).

The use of Panangin together with alcohol causes death in 20% of clinical cases from hypermagnesemia. An increase in the level of a microelement can be stopped by administering calcium gluconate, furosemide or other diuretics.

Reception for a hangover

If you have a hangover, taking Panangin will not relieve headaches or eliminate nausea. It is not suitable for symptomatic treatment and will not quickly relieve a hangover. Taking Panangin will have a minimal effect on the cardiovascular system if the kidneys have previously removed excess fluid and ethanol breakdown products. Therefore, a course of taking the drug can theoretically be started with a hangover, but provided that the alcohol intake the day before was one-time.

In case of hangover, only a doctor can prescribe droppers with Panangin, vitamins B and C, and sodium chloride. This way, the substances will quickly enter the bloodstream and normalize blood pH and electrolyte balance. It is necessary to conduct a clinical study before placing an IV, to find out the amount of electrolytes in the blood (magnesium, potassium, sodium, calcium). Panangin should not be prescribed to patients with persistent withdrawal syndrome due to chronic alcoholism due to increased blood viscosity. These incompatible actions will provoke hyperkalemia and death.

Rules for combining without harm

There are no cases where alcohol can be consumed at the same time as the drug. If the dosage of alcohol does not exceed 20-30 ml per day (fortified drinks) and a person takes no more than two Panangin tablets per day, there will be no harm to the body if consumed simultaneously. Just as there will be no effect from taking the drug. In the case of a combination with spirit, Panangin, entering the body, is immediately excreted in the urine. Therefore, while undergoing treatment with Panangin, you should avoid drinking alcohol, even beer or low-alcohol drinks. The effect of using Panangin can only be obtained the next day after drinking alcohol. This is due to the fact that the main products of ethanol metabolism are excreted by the kidneys within a day.

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The first manifestations of a hangover can be observed within a few hours after drinking alcohol. Increasing headache, rapid heartbeat, loss of orientation in space, chills, fever, dizziness, indigestion - this is not a complete list of symptoms that characterize a person’s morning state after a successful party.

It is not surprising that a person in such a state is ready to use any available means to alleviate the unpleasant and painful symptoms of alcohol poisoning. At the same time, some are “treated” only with proven recipes of traditional medicine, while others rely exclusively on medicines from the home medicine cabinet. Using Asparkam for a hangover, many consider it one of the most effective drugs for restoring vitality and getting rid of the unpleasant symptoms of “morning sickness”. Let's try to figure out if this is so.

How does Asparkam work?

Asparkam (aka Panangin) is a medicine intended to replenish magnesium and potassium in case of their deficiency in the human body. The drug is produced in the form of tablets and ampoules for injection. Depending on this, the main active ingredients are potassium and magnesium aspartate in the first case and magnesium and potassium aspartate in the second. According to the official annotation, the medication is recommended for patients to:

  • lack of microelements in the body;
  • coronary heart disease;
  • chronic circulatory disorders;
  • heart rhythm disturbances.

Panangin helps to quickly restore the balance of electrolytes, eliminate arrhythmia and stabilize metabolic processes in the patient’s body. This means it contributes to the rapid restoration of the patient’s vitality and his speedy recovery.

Important! When taking Asparkam, you should strictly follow your doctor's instructions and dosage. If the medicine is taken independently, you must strictly follow the instructions for the medicine. Do not abuse the tablets or exceed the recommended dosage. Dangerous complications, including death, are possible.

How to combine with alcohol

Alcohol is a strong diuretic. Consequently, it is capable of removing a significant amount of fluid from the human body in a short time. Together with urine, a person loses quite a lot of minerals. Especially potassium and magnesium. This leads to disruption of metabolic processes and malfunctions of organs and systems. At the same time, the concentration of calcium in the blood increases, which is actively washed out of bone tissue. Excess calcium increases hangover symptoms, especially:

  • chills;
  • muscle weakness;
  • increase in temperature;
  • changes in blood pressure;
  • photophobia;
  • nervous excitability.

Important! By taking Panangin for a hangover, you can quickly replenish the lack of potassium and magnesium in the body, which means eliminating painful symptoms and restoring the normal functioning of vital organs. The medicine is especially effective in combination with other drugs that are used to treat alcohol poisoning.

How to take it correctly

The instructions for use included with each package of Asparkam fully describe the drug, indications for use, side effects, dosage, compatibility with other medications and contraindications. When taking the product yourself, you should read the instructions and strictly follow its instructions.

As numerous reviews indicate, it is better to drink Asparkam after cleansing the body of toxins and getting rid of nausea and vomiting. That is, after waking up, you should immediately take a sorbent - Activated Carbon, Enterosgel, Zorex. After this, you can drink green tea, still mineral water, herbal decoction, kefir or yogurt. And only then take Asparkam for a hangover. The correct dosage is 1-2 tablets depending on the severity of symptoms.

Important! If the symptoms are very mild (no nausea and vomiting, frequent urination and diarrhea), you can do without taking the drug. If alcohol poisoning is very severe and the symptoms cannot be alleviated within 2-3 hours, you should immediately call an ambulance. In this situation, taking Asparkam can only do harm.

Contraindications

Along with its beneficial properties, Panangin also has a number of contraindications for use. So, the medicine should not be used if a person has low blood pressure, excess magnesium and calcium in the body, various states of shock, chronic or acute renal failure.

Important! Uncontrolled use of the drug can even cause cardiac arrest! Therefore, before taking Asparkam, it is better to consult a doctor.

Treatment of various diseases with tablets is not limited to a few days. Some drug therapy may take a long time. But the life of every person is filled with various events. For example, anniversaries and holidays require the consumption of alcoholic beverages.

And then the question arises: is it possible to drink alcohol while taking this medicine? To find out how panangin and alcohol will affect your well-being, it is worth studying the processes caused in the human body by each of the substances mentioned.

What is Panangin prescribed for?

The drug Panangin is a representative pharmacological group medications that help the body replenish magnesium-potassium deficiency. The content of the main active components - magnesium and potassium ions is characterized by the following manifestation: potassium deficiency in the plasma blood level is accompanied by a lack of magnesium, as a result of which correction of the content of such substances can be carried out simultaneously. The drug Panangin can compensate for the timely deficiency of these microelements.

This drug complements the complex therapy of ailments caused by myocardial infarction, heart failure, diagnosis of arrhythmia and other abnormalities associated with the cardiovascular system. The high absorption capacity of the drug facilitates its subsequent excretion through the human kidneys.

This drug has some contraindications:

  • chronic kidney disease;
  • decreased urine levels in the body;
  • Myocardial infarction;
  • chronic insufficiency of the adrenal cortex.

After the accumulation of drug components in the body, discomfort, which influence general condition body.

Symptoms:

  • paroxysmal, involuntary muscle contraction due to tension;
  • signs of nausea;
  • increased body temperature;
  • change in color of the epidermis;
  • obstruction of passage respiratory tract;
  • diarrhea.

Is it possible to take Panangin with alcoholic drinks? Instructional rules and warnings from medical specialists exclude the compatibility of panangin with alcohol. This statement is due to the following principles:

  1. 1. This medicine is indicated for patients experiencing abnormalities in the health of the cardiovascular system of the body. Alcohol consumption for this category of patients is contraindicated in any quantity. After drinking alcoholic beverages, the body faces a direct threat of exacerbation of the disease.
  2. 2. By introducing panangin and alcohol into your body at the same time, you can cause a spasmodic process in the blood vessels, disrupting the functioning of the respiratory system. Such an attack must be stopped in time by medical workers. In case of connivance or delay of the phenomenon, you can lose a person.
  3. 3. Alcohol promotes the removal of magnesium and potassium from the body, disrupting the necessary rate of calcium absorption by the body. This is how a person provokes a disruption in his water-salt balance, receiving in return dehydration of the body and loss of important electrolytes.

Panangin against alcohol

Panangin suppresses the effects of impaired health caused by alcohol consumption. In other words, the drug is indicated as an additional means of combination drug therapy alcohol addiction. The compatibility of Panangin with alcohol is not discussed here, because this drug is indicated in the treatment of abstinence, when alcohol is completely removed from the patient’s bloodstream. The essential effect of the medication is aimed at maintaining the important vital functions of the heart muscle.

Some people use panangin after drinking alcohol in the unpleasant stage of a hangover in combination with other drugs. This therapy takes place in the days following alcohol abuse, because the compatibility of Panangin with alcohol is excluded. Contraindications in the instructions for taking Panangin allow for the possibility of dehydration and acidosis. Identical conditions are caused by alcohol, which expresses its negative characteristics in the stage of hangover syndrome.

Possible outcome

Excessive alcohol consumption is the primary cause of acidosis. Symptoms:

  • weakness;
  • gagging;
  • tachycardia;
  • arrhythmia;
  • breathing problems;
  • stressful condition.

This condition is caused by an imbalance in the acid-base level. After a noisy feast, symptoms caused by blood acidification torment the patient. Taking Panangin in a small dosage is useless, and at higher doses the drug will cause negative side effects.

The simultaneous use of panangin with alcoholic beverages can provoke unexpected negative effects. The greatest threat is posed by uncontrolled use of this drug, which causes oversaturation with potassium and magnesium ions, contributing to the development of hyperactivity of these substances in human blood vessels. Therefore, to the question: is it possible to combine panangin and alcohol - there is a clear short answer - NO!

Hyperkalemia

A large concentration of potassium ions is called hyperkalemia. The disease is accompanied by arrhythmia, a violation of the frequency of contractions of the heart muscle. Oversaturation with panangin is accompanied by disorganized myocardial contraction. This condition is characterized by a violation of the blood circulation system. Abundant excess of potassium causes in some cases the cardiac muscle to stop working.

Statistics from medical observations show that during inpatient treatment, abstinence from potassium deficiency, which usually occurs in patients with alcoholism, is eliminated by the administration of potassium chloride. On the first day of treatment for withdrawal symptoms, only 50% of the required amount of this macroelement is administered to avoid the danger of exceeding the dosage. Potassium levels are measured daily.

Hypermagnesemia

Many processes in the human body are magnesium dependent, since this macroelement is considered a necessary participant in the activation of more than three hundred enzymes. A deviation in the concentration of magnesium in the blood plasma provokes a dangerous threat. Panangin with unauthorized alcohol can form an accumulation of magnesium - hypermagnesemia.

An increase in magnesium ions in the blood vessels causes strangulation of the respiratory tract, destruction of the heart muscle, causing the patient to fall into a coma.

Deaths from coronary heart disease and stroke account for about 17.5 million people every year.

In 54% of cases, death occurs due to alcohol abuse.

Violation of water-electrolyte and acid-base balance causes a decrease in protein synthesis in the myocardium by 15%, the development of hypokalemia and hypomagnesemia is observed within 36-72 hours after 50 grams of ethyl alcohol.

In 10% of drinkers, the intoxication state is accompanied by extrasystole and atrial fibrillation; in 25-30% the situation is complicated by atrial and ventricular fibrillation. To restore metabolic processes, it is necessary to regulate the level of potassium and magnesium with the help of medication.

But the drug Panangin is not compatible with alcohol. Therefore, in order not to cause cardiac arrest from a hangover, it is better to choose another effective but safe remedy.

Why take Panangin: features and action


In cardiological practice, the properties of K + and Mg 2+ are widely used to treat pathologies and disorders of the functional functioning of the cardiovascular system. Vital macroelements are responsible for the processes of myocardial excitability, slowing down neural transmission and relaxing smooth muscles.

They provide energy metabolism, maintain the permeability and osmotic pressure of the cell membrane, and participate in the synthesis of proteins, fats and carbohydrates.

Since 2007, the drug known under the trade name Panangin® began to play the role of a source of magnesium and potassium. And in 2015, the manufacturer GEDEON RICHTER released a new drug on the pharmaceutical market with the addition of the word Forte and the dietary supplement Panangin® Plus vitamin B6 to the existing name. For sale and distribution to the population, the pharmaceutical product is presented in tablet form.

Inside each white capsule with a glossy or film surface there are:

  • magnesium, potassium aspartate;
  • povidone K30;
  • corn, potato starch;
  • colloidal silicon dioxide;
  • Magnesium stearate.

Taking into account the original package insert, qualified reviews and the opinion of cardiologists, it is important to take Panangin during complex drug therapy, which is aimed at eliminating K and Mg deficiency in order to prevent heart failure and heart attack.

Against the background of hypokalemia and hypomagnesemia, the medication is used to treat such manifestations as arrhythmia, paroxysmal supraventricular tachycardia, atrial and ventricular extrasystole.

You can speed up the action of Panangin by prescribing a transparent, green-tinged liquid composition for infusion. The concentrate consists of potassium, magnesium ions, and water for injection.

To improve heart rate contractility, restore the ratio of calcium, potassium, magnesium and sodium ions, stop the development of atherosclerosis, hypertension, changes in the myocardium, arrhythmia and enhance the anti-ischemic effect, doctors recommend Panangin.

Be sure to drink it after meals. The daily norm is 1-2 tablets in the morning, lunch and evening. For intravenous injection and drip infusion, dilute the contents of 1-2 ampoules with 5% glucose. Repeat administration is allowed every 4-6 hours.

There is no information that alcohol and Panangin cannot be combined.

Among the contraindications were atrioventricular block II, III degrees, sensitivity to sorbitol and fructose, first trimester of pregnancy, Addison's disease, renal and adrenal insufficiency, cardiogenic shock, arterial hypotension, myasthenia gravis, excess magnesium, potassium.

Side effects include skin flushing, dry mouth, fatigue, dyspeptic disorders, decreased heart rate and even cardiac arrest.

Is it possible to combine alcohol and Panangin?


Due to its physicochemical properties and ability to easily interact with liquid media, ethyl alcohol interferes with all metabolic processes and has a strong toxic effect on the body. In every 4 cases, the cardiovascular system suffers from ethanol.

If Panangin is consumed simultaneously with alcohol, cardiomyocytes begin to be damaged.

Under the influence of alcohol, the activity of sodium excretion increases, which causes the need for oxygen. The transport of potassium into the extracellular space is inhibited.

The interaction of alcohol and Panangin has a cardiodepressive effect. Penetrating into myocardial tissue, ethanol reacts with fatty acids such as oleic, palmitic, linoleic, forming esters.

The high rate of synthesis of toxic compounds activates lipid oxidation and promotes the deposition of amino acids in the tissues of the heart. As a result, heart rate and breathing are suppressed.

About 90% of the breakdown products of acetaldehyde are converted into acetate.

The breakdown of salts increases the load on the liver and energy costs. The oxidation of carbohydrates and fatty acids stops, the level of ammonia in the blood increases, which in high concentrations impedes the excretory function of the kidneys.

The combination of alcoholic beverages and Panangin leads to a retention of uric acid in the body, urolithiasis, and kidney failure.

As part of the plasma, acetaldehyde enters the bloodstream from the biliary system, creating stable connections with the vascular endothelium, structural and functional proteins, and blood cells. Reaching the nervous system, ethanol causes a decrease in calcium in parts of the brain and stimulates the release of large amounts of hormones by the adrenal glands.

The consequence of pathological changes in the endocrine system can be Addison's disease, in which it is strictly forbidden to drink Panangin or combine it with alcohol.

Water-electrolyte imbalance occurs in 30-40% of people diagnosed with alcoholism.

Daily drinking has a negative effect on the secretion of antidiuretic hormone. An increase in the volume of urine excreted stimulates the activity of the renin-angiotensin system, which is directly related to the occurrence of hypertension, difficulty in the absorption of potassium and magnesium, and acid-base imbalance.

Panangin for hangover


Along with the lack of nutrients that leave the body with feces, vomiting and urine, increasing metabolic disorders, against the background of severe myocardial dystrophy and respiratory failure during a hangover, it is better not to even think about taking Panangin.

Characteristic signs of a large hangover are intracellular acidosis, compensatory movement of sodium and hydrogen ions into the cell, excessive activity of the central nervous system and convulsions. If you take Panangin with a hangover, it is possible that the volume of circulating blood and the contractile function of the heart will decrease.

The formation of multiple foci of excitation in parts of the brain and disruption of metabolic energy processes increases the risk of toxic myocardial dystrophy, fibrillation, extrasystole, and arrhythmia.

This is accompanied by the so-called withdrawal or a slowdown in urine formation, or a sharp increase in diuresis with the release of nitrogenous compounds, high acetate production, and symptoms of uremic intoxication.

Despite all the serious consequences, cardiologists, at their own peril and risk, prescribe Panangin for a hangover if the patient has pronounced post-intoxication arterial hypertension.

What could be the consequences of taking it?


Only a qualified specialist, based on the results obtained through laboratory and hardware diagnostics, has the right to decide whether Panangin and alcohol are compatible.

In a healthy person, potassium is part of cells and tissues, plays an important role in ionic balance, conduction of nerve impulses in muscles, normalization of osmotic pressure, dilates the vessels of internal organs and narrows peripheral capillaries, maintains water-salt balance.

The consequence of consuming Panangin after alcohol or with a hangover can be hyperkalemia.

It is associated with the entry of a high concentration of K + into the bloodstream and the body’s inability to absorb the macronutrient. It occurs due to deterioration of the urinary system, decreased sensitivity of the receptors of the distal tubules of the kidneys, and manifests itself in the case of intracellular acidosis, ischemia, hypoxia, and damage to cell membranes.

In patients, it is accompanied by muscle weakness, tachycardia, bradycardia and arrhythmia.

Hypermagnesemia– a complication that appears after the interaction of Panangin and alcoholic beverages.

An increase in magnesium in the blood serum occurs due to the redistribution of the macroelement from cells into the intercellular fluid, impaired absorption of the intestine, dyspeptic disorders, inhibition of the activity of neurons in the respiratory center, chronic acidosis, arterial hypotension, and renal failure.

In the absence of timely and adequate treatment, hyperkalemia and hypermagnesemia result in cardiac arrest and death. Therefore, before starting use, you need to undergo consultation and approval of the treating doctor.

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